Spring Semester 2013 (Bioprocess Engineering, ChE453)
Green Hall L0159 Schedule: Tuesday and Thursday: 10~11:30am
Office Hours: 11:30–1:30 Tuesday and Thursday TA: Lian He (Computer Lab Instructor)
This course not only gives an overview of bioprocess engineering fundamentals, but also focuses on: 1. how systems biology and molecular biology have been applied to understand cellular metabolisms and to induce cellular production of useful compounds; 2. how modeling approaches can be used to analyze and optimize the bioprocesses; 3. Bioprocessing applications related to bioenergy.
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Date |
Topics |
Date |
Topics |
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Jan 15 |
Introduction to ME and Biological Basics |
Jan 17 |
Biochemistry and enzymology overview |
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Jan 22 |
Enzyme kinetics |
Jan 24 |
Genetics and cellular regulation (presentation: Balassy, Andrea) |
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Jan 29 |
Central pathways (Henson, William ) |
Jan 31 |
Cell metabolism (Hollinshead, Whitney ) |
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Feb 5 |
Cell metabolism (Hoynes-O'Connor, Allison) |
Feb 7 |
Microbial Metabolic diversity (Kading, Jacqueline) |
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Feb 12 |
Bio-reaction models (Kim, Doyoon) |
Feb 14 |
Bio-reaction models (Oxford, Christopher ) |
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Feb 19 |
Stoichiometry (Shopera, Tatenda) |
Feb 21 |
Metabolic flux analysis (Vazquez, Miguel) |
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Feb 26 |
Bioprocess operation (Xiong, Wei) |
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Bioprocess operation/separation (Yeh, Hsi-Wei) |
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Mar 5 |
Bioseparation and class overview(Zhang, Lijie) |
Mar 7 |
Midterm due (close book) |
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Note: Spring break (Mar 12 and 14). The location of computer lab from Mar 19~April 2 is in Lopata 401 |
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Mar 19 |
Computer Lab (MATLAB basic) |
Mar 21 |
Computer (ODEs) |
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Mar 26 |
Computer Lab (PDEs) |
Mar 28 |
Computer Lab (Process Optimization) |
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April 2 |
Computer Lab (Parameter estimation) |
April 4 |
Functional genomics methods (Philip) |
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April 9 |
Functional genomics methods (Jared) |
April 11 |
Nonconventional biologic systems (Yu) |
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April 16 |
Life Cycle Analysis (By Mark Henson) |
April 18 |
Biofuel Process (from pretreatment to fermentation) |
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April 23
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Biofuel Process (2 and 3 generation biofuel) |
April 25 |
Student Presentations (4 groups) |
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Presentation group 1: Whitney, Wei and Allie (light activated biosensors ) Presentation group 2: Hsi-Wei, Doyoon, and Tatenda
Final Take-Home Exam is assigned on April 23 and due on April 30 (Tuesday by 12pm) |
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Note:
I highly recommend you to attend EECE 595C-BioMolecular Engineering lectures (taught by Fuzhong Zhang). You may just sit in the class without registration. . It will be very helpful for your PhD research, and it will also be helpful for your qualify exam. This class is on Tuesday and Thursdays (5:30PM-7:00PM; Lopata Hall 302 ). The class's schedule is below.
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Fall Semester 2012
Process Control Che462 (Fall 2012) : 9am ~ 10am, Green Hall 0160
(Monday, Wednesday and Friday)
Tang Office: Brauer Hall 1025; TA Lian Office: Brauer Hall 1043
Help session: Green Hall 0160 (7pm – 8pm; Tuesdays, Sept.4 ~ Nov. 2)
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Class Outline Week 1 slides (HW1: 1.1; 1.3; 1.7; 2.1; 2.3; 2.13, 9.1, 9.2, Due on Sept 7 )
Week 2 slides (HW2: 2.14 (a, b), 2.17, 10.3, 3.4, 3.6, 3.11, Due on Sept 14 )
Week 3 slides (Quiz on Sept 14)
Week 4 slides (HW3: 3.14, 3.16(a), 4.1; 4.2; 4.5, Due on Sept 24)
Week 5 slides (HW4: 4.15; 5.2; 5.6; 5.12; 5.24; 5.27; 6.14, 6.20, 7.3, Due on Oct 5)
Week 6 slides (Midterm October 8) Key points in Midterm: 1.Mass and Heat balance models; 2.Laplace Transform and final value/initial value theory; 3.Poles and zeros and their effect on process responses; 4. Linearization and find transfer function; 5.First order and second order processes responses to inputs;
6.Model simplification via time delay Excel File for ODEs Useful Links: http://www.wolframalpha.com/ http://eqworld.ipmnet.ru/
Week 7 slides (HW5: 6.23 (a, b, c); 7.9; 8.2; 8.3; 8.6; 8.15; 11.1; Due on Oct 17)
Week 8 slides (HW6: 11.3; 11.10; 11.13; 11.14; 12.1, 12.3 (a, b); Due on Oct 26)
Week 9 slides (HW7: 13.1, 13.2, 14.1, 14.3, 14.4, 15.5 (b); 16.2 ; Due on Nov 9)
Week 10 (Guest lecture 1 by Professor Heider; Guest lecture 2 by Professor Zhang; Quiz 3)
Week 11 Slides
Computer Lab since Nov 9 (Urbauer 218 )
Simulink tutorial Matlab and Simulink Lecture Part 1 (Computer programs)
Matlab Lecture Part 2 (Optimization and Parameter Fitting Programs)
Project 1 (Due on November 19th)
Project 2 and data sheet for Q2 (Due on December 3)
Lecture Notes
Presentation schedule
Final Exam:
Dec 14 (8:00am~10am, normal schedule, Green Hall 0160)
Final Exam Coverage
2011 Class with KirK Dolan: . http://tang.eece.wustl.edu/MATLAB_WUSTL.htm