Teaching at Washington University

Process Control ChE462 (2008, 2009, 2010, 2011, 2012, 2013, 2014)

Bioprocess Engineering ChE453 (2013, 2014, 2015)

Fluid Mechanics Transport 1 ChE367 (2013, co-teaching)

Metabolic Engineering ChE596 (2010, 2011, 2012)

International Experience EECE401 (2012 in Brazil, co-teaching)

Advanced Energy Lab EECE439 (2011, co-teaching)

**Class in 2015**

**Bioprocess Engineering ChE 453 Classroom: Whitaker
216; Tuesday and Thursday: 10~11:30 am **

Tang Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours: 11:30–1:30 Tuesday and Thursday

TA: Wen Jiang (Brauer Hall 1044). TA office hour: 2~5pm, Monday

HW1: Text book, 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16, 3.1

HW2: 3.2, 3.3, 3.5, 3.7, 3.9, 3.13, 3.16, 3.17

HW3: 4.2, 4.3, 4.4, 4.6, 5.1, 5.3, 5.6, 5.7, 5.9, 5.11, 6.1, 6.3, 6.5, 6.9, 6.17(note: biomass yield Y = 0.4 g X/g S)

HW4: 7.2, 7.4, 7.5, 8.3, 8.7, 8.10, and Midterm Long Question 4 (using MATLAB to solve Fungal fermentation, you need to develop a model then use parameter fitting to find the model parameters).

HW5: 9.1, 9.2, 9.10, 9.12, 10.2; 10.15; 11.2 (Due April 7)

HW6: 12.3; 12.4; 12.5; 13.3; 14.3; 14.8; 16.1 (Due April 14)

Date |
Topics |
Date |
Topics |

Jan 13 |
Introduction to Biological Basics |
Jan 15 |
Biochemistry overview |

Jan 20 |
Biochemistry Overview (HW1 due) |
Jan 22 |
Enzyme kinetics |

Jan 27 |
Enzyme kinetics |
Jan 29 |
Cellular process and regulations |

Feb 3 |
Metabolism (HW2 due) |
Feb 5 |
Metabolism |

Feb 10 |
Cell metabolism |
Feb 12 |
Microbial bioenergetics |

Feb 17 |
Cell growth models(yield, titer, rate) |
Feb 19 |
Cell growth models (HW3 due) |

Feb 24 |
Molecule biology basics (Wen) |
Feb 26 |
Midterm (Chapter 1~9) |

Mar 3 |
Stoichiometry models |
Mar 5 |
Bioreactor models and flux model |

Mar 17 |
MATLAB overview (Lian) |
Mar 19 |
Reactor model and Flux model |

Mar 24 |
Bioreactor Operation (HW4 due) |
Mar 26 |
Bioreactor Operations and Control |

Mar 31 |
Bio-separation |
April 2 |
Animal/Plant Culture/mixed cultures |

April 7 |
Systems biotechnology (HW5 due) |
April 9 |
Biofuel Process |

April 14 |
Biofuel Process (HW 6 due) |
April 16 |
Final Exam part 1 |

April 21 |
Student Presentations (5 groups) |
April 23 |
Overview and Qualify exam |

(Final Exam Part 2 is due on April 27; there is a special help session for PhD Q-exam on May 5) |

**Journal club schedule: introduce any hot topics
related to metabolic engineering **

**(10 minute presentation, at the beginning of class)
**

Date |
Names |
Date |
Names |

Jan 27 |
Mary |
Jan 29 |
Yeunook |

Feb 3 |
Wei |
Feb 5 |
Merima |

Feb 10 |
Mariah |
Feb 13 |
Drew |

Feb 17 |
TBD |
Feb 19 |
Katherine |

Feb 24 |
ND |
Feb 26 |
Midterm |

Mar 3 |
Charles |
Mar 5 |
Anna |

Mar 17 |
Kevin |
Mar 19 |
Chiamaka |

Mar 24 |
Tola |
Mar 26 |
Nathan |

Mar 31 |
Imani |
April 2 |
Zongshen |

**Classes in 2014****
**

ChE 462 - Chemical Process Dynamics and Control (Aug 25~Dec 12)

Topics: steady and unsteady-state behavior of chemical processes; fundamental feedback and feedfoward control strategies; modern control theory and applications; process modeling and problem solving with Excel, MATLAB and Simulink.

Class Time 9 – 10 MWF (Green Hall 0160)

Help session 7 – 8 pm (Tuesdays)

Computer Lab Urbauer 218

Instructor Office Hours: 10:00–11:00 Monday, Wednesday and Friday

Teaching Assistant: He Jing, Brauer Hall 3044; Email: he.jing@wustl.edu ;

Whitney Hollinshead, Brauer Hall 1044; Email: whollinshead@wustl.edu ;

TA Office hours: 2:00–5:00 pm (He, Wednesday); 2:00–5:00 pm (Whitney, Thursday)

**Field Trip to Wood River Refinery - Phillips 66 (8~11am,
Dec 9)**

***************************************************************************

Bioprocess Engineering ChE 453

Classroom: Green Hall L0160 (Classes during March 18~April 1 will be in the computer lab)

Schedule: Tuesday and Thursday: 10~11:30 am (Journal club: In each class, one student will have a ten-minute presentation at the beginning of the class)

Yinjie Tang (Instructor) Email: yinjie.tang@seas.wustl.edu Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours: 11:30–1:30 Tuesday and Thursday TA: Ray Henson (Computer Lab Instructor)

Homework 1: Text book: 1.2, 1.3, 2.2, 2.4; 2.5; 2.6; 2.8; 2.12; 2.16; 3.1

Homework 2: Text book: 3.2, 3.5, 3.9, 3.17, 4.2, 4.3, 4.4 Due on Feb 6

Homework 3: Text book: 5.6.; 5.7; 5.9; 5.11; 6.1; 6.5; 6.9; 7.2; 7.4 Due on Feb 20

Homework 4: Due on April 22nd.

Homework 5: Textbook: 11.2 and 11.3; 12.3, 12.4, 12.5, 13.3, 14.8. Due on April 24th.

Fall, 2013 (I teach two undergraduate classes)

Process Dynamics and Control ChE462

Class Room Rudolph 203; Time: 9am ~ 10am (Monday, Wednesday and Friday)

Help session: Green Hall 0159 (7pm – 8pm; Tuesdays, Sept.10 ~ Nov. 5)

Instructor Office Hours (Brauer Hall 1025):10:00–11:00 (Mon, Wed and Fri)

TA: Cheryl Immethun; Email: cheryl.immethun@wustl.edu; Office hours:4:30–6:00 pm, Tue and Thur (Brauer Hall 3046)

Useful Links: http://www.wolframalpha.com/ ; http://eqworld.ipmnet.ru/

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Fluid Mechanics (Transport 1, ChE367)

Tuesday and Thursday from 1pm-2:30pm (Classroom: Lopata 101); Office Hour (Brauer Hall 1025, 4~5pm, Monday)

Help Session: Brauer Hall 3015, 5:30pm-6:30pm Tuesday; Brauer Hall 3014, 5:30pm-6:30pm Wednesday

TA: Chris Oxford: Ph(314-935-7970), Email: coxford@wustl.edu; Mike Kuan-Yu Shen: Ph(314-935-7563), Email: kys9466@gmail.com

Class notes: Part 1; Part 2; Part 3

**Course Coverage**

9-3-2013 and before: Laminar vs turbulent flow; Reynolds number: Flow transition criteria; Friction factor: Darcy and Fanning definitions; Pipe roughness parameter; Friction factor charts: Some mathematical representations of the same; Pipe flow pressure drop calculations for a given flow; Pipe flow rate calculations given a pressure drop; Concept of fully developed flow; Relation between wall shear stress and pressure drop for a fully developed flow

9-5-2013: Newtonain vs non-Newtonain fluids; Bulk modulus; Speed of sound Mach number; Incompressibilty criteria; Surface tension; Contact angle; Level rise in a capillary; Laplace-Young equation; Pressure inside a bubble; Normal vs shear stress; Pressure as a scalar: Pascal’s law Equation of hydrostatics

9-10-13: Archimedus principle; Pressure variation in a column of gas; Pressure variation in a column of liquid; Pressure force on a plane surface; Center or pressure concept; Pressure force on a curved surface

9-12-13: Linear acceleration; Rigid body rotation; Compressible gas pressure with depth; Resultant force on a plane surface

9-17(19)-13: Newton second law; Streamlines in steady flow; Streamwise acceleration Normal acceleration; ;Newton’s law along a streamline; Bernoulli equation; Newton’s law normal to a streamline; Stagnation point and pressure

9-24-13 : Pressure profile in a tornado; Continuity equation; Pitot tube analysis; Free jet and draining of a tank; Flow meter equation; Sluice gate equation; Use of head balance; Head due to turbine or pump; Head due to friction

9-26-13 : Modified Bernoulli equation; Sudden expansion; Cavitation; Bernoulli for unsteady flow; Acceleration of a fluid particle: General derivation; Streamline calculation for 2-D steady state flows

10-1-13 : Oscillating manometer; Bernoulli for compressible fluids; Example: Working rate needed for a compressor; Macroscopic momentum balances; Sudden expansion revisited

10-3-13 : Jet flowing along a vane; Rocket acceleration analysis; Sluice gate momentum balance; Momentum correction factor; Angular momentum balance

10-8-13: Macroscopic balances examples

10-10-13 : Angular momentum: Examples; Energy equation; Converging-diverging nozzle

10-17-13 (Midterm in class, Open notes)

10-22-13: Velocity field, Eulerian and Lagrangian flow description, streakline/pathline/streamline, Steady flow

10-24-13: Acceleration field and unsteady effects, Concept of streamline coordinates

10-29-13: Reynolds Transport Theorem, Fluid element motion and deformation, Volumetric dilatation, Angular motion and fluid rotation/irrotation, Conservation of mass and continuity equation

10-31-13: Continuity equations for incompressible fluid, Cylindrical coordinate, Stream function/Streamlines, Conservation of linear Momentum (Euler's Equation of motion), The concept of the Navier-Stokes equation, Bernoulli Equation, Simplification of Navier-Stokes equation.

11-5-13: Velocity potential, Laplace equation, Source-sink pair, Simple solutions for fluids, Assumption of Bernoulli equation

11-12-13 : Model simplification via dimensionless variables, Re number, Froude number

11-14-13: Pipe flow, Laminar and Turbulent flow (By Chris)

11-19-13: Poiseuille's Law, Fully developed flow, Laminar flow pressure drop, Turbulent flow shear stress, Viscous sublayer, Dimensional Analysis of pipe flow

11-21-13: Turbulent velocity profiles (three regions), Turbulent pressure drop, Roughness, Major and minor head loss, Modified Bernoulli equation, Moody chart, Flow rate Measurement (orifice or nozzle meter)

11-26-13/Dec-3-13: Laminar and turbulent flow over immersed bodies; Life and Drag coefficients; Boundary layer definitions, Boundary layer separation, Effect of Re on Drag,

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**WUSTL and MSU are working together to improve
teaching in systems biology. **

Dolan KD, Tang YJ, Liao W “Improvement of Bioengineering Courses through Systems Biology and Bioprocess Modeling”. 121 Annual conference of American Society for Engineering Education. Indiana. 2014.

http://www.asee.org/public/conferences/32/registration/view_session?session_id=3412 (if the link does not work directly, you can copy and paste it into a new window).

**We shared Class Materials with
Dr. Wei Liao and Dr. Kirk Dolan from Michigan State**** University. More MATLAB
lectures can be found at the website below:**