Teaching at Washington University

Process Control ChE462 (2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016);

Bioprocess Engineering ChE453 (2013, 2014, 2015, 2017);

Fluid Mechanics Transport 1 ChE367 (2013);

Metabolic Engineering ChE596 (2010, 2011, 2012);

International Experience EECE401 (2012 in Brazil);

Advanced Energy Lab EECE439 (2011)



Bioprocess Engineering


Bioprocess Engineering ChE 506
Classroom:    Sever Hall 300; Tuesday and Thursday: 5:30~7:00 pm

Yinjie Tang (Instructor) Email: yinjie.tang@wustl.edu

Ryan Lee (TA, Brauer Hall 1047); Email: vitamincwater@gmail.com 

Office: Brauer Hall 1025 (Phone:314-935-3441)

Office Hours for Dr. Tang:   4:30–5:30 Tuesday and Thursday

TA office hours (You can email TA and make an appointment)




HW1 (Due Jan 26):   Text Book: 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16      












Process Control 401


Class Time : 9–10 MWF ; Classroom :  Lopata Hall 101 (Computer Lab in Ubuer 218); Help session : Whitaker 216 (7 – 8 pm, Tuesdays)

 TA:  Dishant Khatri; Email: dishant@wustl.edu; Brauer Hall  3039;  Tolutola Oyetunde; Email: toyetunde@wustl.edu ; Brauer Hall 1042 


Coverage: Model development and simplifications; Dynamics of first order and second order process (including time delays); Determine the process features based on the roots of characteristic equation; Draw and analyze systems using block diagram ; Develop transfer functions based on block diagram; Stability analysis and process safety ; P-I-D control features and design ; Feedforward ; Cascade control ; Simulink and MATLAB questions; Frequency responses


Final Exam (Lopata Hall 101, 8-10am, Dec 16)


1.  Dynamics of first order and second order process (including time delays)

2.  Determine the process features based on the roots of characteristic equation

3.  Draw and analyze systems using block diagram

4.  Develop transfer functions based on block diagram

5.  Stability analysis, process safety and Ruth array

6.  P-I-D control features and design

7.  Feed forward and cascade control

8.  Simulink and MATLAB questions

9.  Frequency responses

10. Class presentation questions





Class in 2015: Bioprocess Engineering ChE 453 Classroom:  Whitaker 216; Tuesday and Thursday: 10~11:30 am

Tang Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours: 11:30–1:30 Tuesday and Thursday

TA:  Wen Jiang (Brauer Hall 1044).    TA office hour: 2~5pm, Monday


HW1: Text book, 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16, 3.1

HW2:  3.2, 3.3, 3.5, 3.7, 3.9, 3.13, 3.16, 3.17

HW3: 4.2, 4.3, 4.4, 4.6, 5.1, 5.3, 5.6, 5.7, 5.9, 5.11, 6.1, 6.3, 6.5, 6.9,  6.17(note: biomass yield Y = 0.4 g X/g S)

HW4: 7.2, 7.4, 7.5, 8.3, 8.7, 8.10, and Midterm Long Question 4 (using MATLAB to solve Fungal fermentation, you need to develop a model then use parameter fitting to find the model parameters).

HW5: 9.1, 9.2, 9.10, 9.12, 10.2; 10.15;  11.2 (Due April 7)

HW6: 12.3; 12.4; 12.5; 13.3; 14.3; 14.8; 16.1 (Due April 14)


Fluid Mechanics (Transport 1, ChE367)

Tuesday and Thursday from 1pm-2:30pm (Classroom: Lopata 101); Office Hour (Brauer Hall 1025, 4~5pm, Monday)

Help Session: Brauer Hall 3015, 5:30pm-6:30pm Tuesday; Brauer Hall 3014, 5:30pm-6:30pm Wednesday

 TA: Chris Oxford: Ph(314-935-7970), Email: coxford@wustl.edu; Mike Kuan-Yu Shen: Ph(314-935-7563), Email: kys9466@gmail.com

Class notes:  Part 1Part 2; Part 3

Course Coverage

9-3-2013 and before: Laminar  vs  turbulent flow; Reynolds number: Flow transition criteria; Friction factor: Darcy and Fanning definitions; Pipe roughness parameter; Friction factor charts: Some mathematical representations of the same; Pipe flow pressure drop calculations for a given flow; Pipe flow rate calculations given a pressure drop; Concept of fully developed flow; Relation between wall shear stress and pressure drop for a fully developed flow  

9-5-2013: Newtonain vs non-Newtonain fluids; Bulk modulus; Speed of sound Mach number; Incompressibilty criteria; Surface tension; Contact angle; Level rise in a capillary; Laplace-Young equation; Pressure inside a bubble; Normal vs shear stress; Pressure as a scalar: Pascal’s law Equation of hydrostatics

9-10-13: Archimedus principle; Pressure variation in a column of gas; Pressure variation in a column of liquid; Pressure force on a plane surface; Center or pressure concept; Pressure force on a curved surface

9-12-13: Linear acceleration; Rigid body rotation; Compressible gas pressure with depth; Resultant force on a plane surface

9-17(19)-13: Newton second law; Streamlines in steady flow; Streamwise acceleration Normal acceleration; ;Newton’s law along a streamline; Bernoulli equation; Newton’s law normal to a streamline; Stagnation point and pressure  

9-24-13 : Pressure profile in a tornado; Continuity equation; Pitot tube analysis; Free jet and draining of a tank; Flow meter equation; Sluice gate equation; Use of head balance; Head due to turbine or pump; Head due to friction   

9-26-13 : Modified Bernoulli equation; Sudden expansion; Cavitation; Bernoulli for unsteady flow; Acceleration of a fluid particle: General derivation; Streamline calculation for 2-D steady state flows

10-1-13 : Oscillating manometer; Bernoulli for compressible fluids; Example: Working rate needed for a compressor; Macroscopic momentum balances; Sudden expansion revisited      

10-3-13 : Jet flowing along a vane; Rocket acceleration analysis; Sluice gate momentum balance; Momentum correction factor; Angular momentum balance

10-8-13: Macroscopic balances examples    

10-10-13 : Angular momentum: Examples; Energy equation; Converging-diverging nozzle

10-17-13 (Midterm in class, Open notes)

10-22-13: Velocity field, Eulerian and Lagrangian flow description, streakline/pathline/streamline, Steady flow

10-24-13: Acceleration field and unsteady effects, Concept of streamline coordinates

10-29-13: Reynolds Transport Theorem, Fluid element motion and deformation, Volumetric dilatation, Angular motion and fluid rotation/irrotation, Conservation of mass and continuity equation

10-31-13: Continuity equations for incompressible fluid, Cylindrical coordinate, Stream function/Streamlines,  Conservation of linear Momentum (Euler's Equation of motion), The concept of the Navier-Stokes equation, Bernoulli Equation, Simplification of Navier-Stokes equation.

11-5-13: Velocity potential, Laplace equation, Source-sink pair, Simple solutions for fluids, Assumption of Bernoulli equation

11-12-13 : Model simplification via dimensionless variables, Re number, Froude number

11-14-13: Pipe flow, Laminar and Turbulent flow (By Chris)

11-19-13: Poiseuille's Law, Fully developed flow, Laminar flow pressure drop, Turbulent flow shear stress, Viscous sublayer, Dimensional Analysis of pipe flow

11-21-13: Turbulent velocity profiles (three regions), Turbulent pressure drop, Roughness, Major and minor head loss, Modified Bernoulli equation, Moody chart, Flow rate Measurement (orifice or nozzle meter)

11-26-13/Dec-3-13: Laminar and turbulent flow over immersed bodies; Life and Drag coefficients; Boundary layer definitions, Boundary layer separation, Effect of Re on Drag, 


WUSTL and MSU are working together to improve teaching in systems biology.

Dolan KD, Tang YJ, Liao W “Improvement of Bioengineering Courses through Systems Biology and Bioprocess Modeling”. 121 Annual conference of American Society for Engineering Education. Indiana. 2014. 



We shared Class Materials with Dr. Wei Liao and Dr. Kirk Dolan from Michigan State University. More MATLAB lectures can be found at the website below: http://tang.eece.wustl.edu/MATLAB_WUSTL.htm