Teaching at Washington University    

Process Control ChE462 (2008, 2009, 2010, 2011, 2012, 2013, 2014)

Bioprocess Engineering ChE453 (2013, 2014, 2015)

Fluid Mechanics Transport 1 ChE367 (2013, co-teaching)

Metabolic Engineering ChE596 (2010, 2011, 2012)

International Experience EECE401 (2012 in Brazil, co-teaching)

Advanced Energy Lab EECE439 (2011, co-teaching)



Class in 2015

Bioprocess Engineering ChE 453 Classroom:  Whitaker 216; Tuesday and Thursday: 10~11:30 am

Tang Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours: 11:30–1:30 Tuesday and Thursday

TA:  Wen Jiang (Brauer Hall 1044).    TA office hour: 2~5pm, Monday


HW1: Text book, 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16, 3.1

HW2:  3.2, 3.3, 3.5, 3.7, 3.9, 3.13, 3.16, 3.17

HW3: 4.2, 4.3, 4.4, 4.6, 5.1, 5.3, 5.6, 5.7, 5.9, 5.11, 6.1, 6.3, 6.5, 6.9,  6.17(note: biomass yield Y = 0.4 g X/g S)

HW4: 7.2, 7.4, 7.5, 8.3, 8.7, 8.10, and Midterm Long Question 4 (using MATLAB to solve Fungal fermentation, you need to develop a model then use parameter fitting to find the model parameters).

HW5: 9.1, 9.2, 9.10, 9.12, 10.2; 10.15;  11.2 (Due April 7)

HW6: 12.3; 12.4; 12.5; 13.3; 14.3; 14.8; 16.1 (Due April 14)







Jan 13

Introduction to Biological Basics

Jan 15

Biochemistry overview

Jan 20

Biochemistry Overview (HW1 due)

Jan 22

 Enzyme kinetics

Jan 27

Enzyme kinetics

Jan 29

Cellular process and regulations

Feb 3

Metabolism (HW2 due)

Feb 5


Feb 10

Cell metabolism

Feb 12

Microbial bioenergetics

Feb 17

Cell growth models(yield, titer, rate)

Feb 19

Cell growth models (HW3 due)

Feb 24

Molecule biology basics (Wen)

Feb 26

Midterm (Chapter 1~9)

Mar 3

Stoichiometry models

Mar  5

Bioreactor models and flux model

Mar 17

MATLAB overview (Lian)

Mar 19

Reactor model and Flux model

Mar 24

Bioreactor Operation (HW4  due)

Mar 26

Bioreactor Operations and Control

Mar 31


April 2

 Animal/Plant Culture/mixed cultures

April 7

Systems biotechnology (HW5 due)

April 9

Biofuel Process

April 14

Biofuel Process (HW 6 due)

April 16

Final Exam part 1

April 21

Student Presentations (5 groups)

April 23

Overview and Qualify exam

(Final Exam Part 2 is due on April 27; there is a special help session for PhD Q-exam on May 5)



Journal club schedule: introduce any hot topics related to metabolic engineering

(10 minute presentation, at the beginning of class)





Jan 27


Jan 29


Feb 3


Feb 5


Feb 10


Feb 13


Feb 17


Feb 19


Feb 24


Feb 26


Mar 3


Mar  5


Mar 17


Mar 19


Mar 24


Mar 26


Mar 31


April 2






Classes in 2014   

ChE 462 - Chemical Process Dynamics and Control  (Aug 25~Dec 12)

 Topics: steady and unsteady-state behavior of chemical processes; fundamental feedback and feedfoward control strategies; modern control theory and applications; process modeling and problem solving with Excel, MATLAB and Simulink.  

Class Time                     9 – 10 MWF (Green Hall 0160)

Help session                   7 – 8 pm   (Tuesdays)                                                

Computer Lab                Urbauer 218

Instructor Office Hours:   10:00–11:00 Monday, Wednesday and Friday  

Teaching Assistant:         He Jing, Brauer Hall 3044;  Email: he.jing@wustl.edu ;

                                      Whitney Hollinshead,  Brauer Hall 1044; Email: whollinshead@wustl.edu  ;

TA Office hours:             2:00–5:00 pm (He, Wednesday);    2:00–5:00 pm (Whitney, Thursday)

Field Trip to Wood River Refinery - Phillips 66 (8~11am, Dec 9)




Bioprocess Engineering ChE 453

Classroom: Green Hall L0160 (Classes during March 18~April 1 will be in the computer lab)

Schedule: Tuesday and Thursday: 10~11:30 am (Journal club: In each class, one student will have a ten-minute presentation at the beginning of the class)

Yinjie Tang (Instructor) Email: yinjie.tang@seas.wustl.edu Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours:   11:30–1:30 Tuesday and Thursday TA:  Ray Henson (Computer Lab Instructor)

Homework 1: Text book: 1.2, 1.3, 2.2, 2.4; 2.5; 2.6; 2.8; 2.12; 2.16; 3.1

Homework 2: Text book: 3.2, 3.5, 3.9, 3.17, 4.2, 4.3, 4.4       Due on Feb 6

Homework 3: Text book: 5.6.; 5.7; 5.9; 5.11; 6.1; 6.5; 6.9; 7.2; 7.4  Due on Feb 20  

Homework 4: Due on April 22nd.

Homework 5: Textbook: 11.2 and 11.3; 12.3, 12.4, 12.5, 13.3, 14.8. Due on April 24th.


Fall, 2013 (I teach two undergraduate classes)

Process Dynamics and Control ChE462

Class Room Rudolph 203; Time: 9am ~ 10am (Monday, Wednesday and Friday)

Help session:  Green Hall 0159  (7pm – 8pm;  Tuesdays, Sept.10 ~ Nov. 5)

Instructor Office Hours (Brauer  Hall 1025):10:00–11:00 (Mon, Wed and Fri)

TA: Cheryl Immethun; Email: cheryl.immethun@wustl.edu; Office hours:4:30–6:00 pm, Tue and Thur (Brauer Hall 3046)

Useful Links: http://www.wolframalpha.com/   ; http://eqworld.ipmnet.ru/     



Fluid Mechanics (Transport 1, ChE367)

Tuesday and Thursday from 1pm-2:30pm (Classroom: Lopata 101); Office Hour (Brauer Hall 1025, 4~5pm, Monday)

Help Session: Brauer Hall 3015, 5:30pm-6:30pm Tuesday; Brauer Hall 3014, 5:30pm-6:30pm Wednesday

 TA: Chris Oxford: Ph(314-935-7970), Email: coxford@wustl.edu; Mike Kuan-Yu Shen: Ph(314-935-7563), Email: kys9466@gmail.com

Class notes:  Part 1Part 2; Part 3

Course Coverage

9-3-2013 and before: Laminar  vs  turbulent flow; Reynolds number: Flow transition criteria; Friction factor: Darcy and Fanning definitions; Pipe roughness parameter; Friction factor charts: Some mathematical representations of the same; Pipe flow pressure drop calculations for a given flow; Pipe flow rate calculations given a pressure drop; Concept of fully developed flow; Relation between wall shear stress and pressure drop for a fully developed flow  

9-5-2013: Newtonain vs non-Newtonain fluids; Bulk modulus; Speed of sound Mach number; Incompressibilty criteria; Surface tension; Contact angle; Level rise in a capillary; Laplace-Young equation; Pressure inside a bubble; Normal vs shear stress; Pressure as a scalar: Pascal’s law Equation of hydrostatics

9-10-13: Archimedus principle; Pressure variation in a column of gas; Pressure variation in a column of liquid; Pressure force on a plane surface; Center or pressure concept; Pressure force on a curved surface

9-12-13: Linear acceleration; Rigid body rotation; Compressible gas pressure with depth; Resultant force on a plane surface

9-17(19)-13: Newton second law; Streamlines in steady flow; Streamwise acceleration Normal acceleration; ;Newton’s law along a streamline; Bernoulli equation; Newton’s law normal to a streamline; Stagnation point and pressure  

9-24-13 : Pressure profile in a tornado; Continuity equation; Pitot tube analysis; Free jet and draining of a tank; Flow meter equation; Sluice gate equation; Use of head balance; Head due to turbine or pump; Head due to friction   

9-26-13 : Modified Bernoulli equation; Sudden expansion; Cavitation; Bernoulli for unsteady flow; Acceleration of a fluid particle: General derivation; Streamline calculation for 2-D steady state flows

10-1-13 : Oscillating manometer; Bernoulli for compressible fluids; Example: Working rate needed for a compressor; Macroscopic momentum balances; Sudden expansion revisited      

10-3-13 : Jet flowing along a vane; Rocket acceleration analysis; Sluice gate momentum balance; Momentum correction factor; Angular momentum balance

10-8-13: Macroscopic balances examples    

10-10-13 : Angular momentum: Examples; Energy equation; Converging-diverging nozzle

10-17-13 (Midterm in class, Open notes)

10-22-13: Velocity field, Eulerian and Lagrangian flow description, streakline/pathline/streamline, Steady flow

10-24-13: Acceleration field and unsteady effects, Concept of streamline coordinates

10-29-13: Reynolds Transport Theorem, Fluid element motion and deformation, Volumetric dilatation, Angular motion and fluid rotation/irrotation, Conservation of mass and continuity equation

10-31-13: Continuity equations for incompressible fluid, Cylindrical coordinate, Stream function/Streamlines,  Conservation of linear Momentum (Euler's Equation of motion), The concept of the Navier-Stokes equation, Bernoulli Equation, Simplification of Navier-Stokes equation.

11-5-13: Velocity potential, Laplace equation, Source-sink pair, Simple solutions for fluids, Assumption of Bernoulli equation

11-12-13 : Model simplification via dimensionless variables, Re number, Froude number

11-14-13: Pipe flow, Laminar and Turbulent flow (By Chris)

11-19-13: Poiseuille's Law, Fully developed flow, Laminar flow pressure drop, Turbulent flow shear stress, Viscous sublayer, Dimensional Analysis of pipe flow

11-21-13: Turbulent velocity profiles (three regions), Turbulent pressure drop, Roughness, Major and minor head loss, Modified Bernoulli equation, Moody chart, Flow rate Measurement (orifice or nozzle meter)

11-26-13/Dec-3-13: Laminar and turbulent flow over immersed bodies; Life and Drag coefficients; Boundary layer definitions, Boundary layer separation, Effect of Re on Drag, 





WUSTL and MSU are working together to improve teaching in systems biology.

Dolan KD, Tang YJ, Liao W “Improvement of Bioengineering Courses through Systems Biology and Bioprocess Modeling”. 121 Annual conference of American Society for Engineering Education. Indiana. 2014. 

http://www.asee.org/public/conferences/32/registration/view_session?session_id=3412   (if the link does not work directly, you can copy and paste it into a new window).


We shared Class Materials with Dr. Wei Liao and Dr. Kirk Dolan from Michigan State University. More MATLAB lectures can be found at the website below: