Teaching at Washington University

Process Control ChE462 (2008, 2009, 2010, 2011, 2012, 2013, 2014, 2015, 2016);

Bioprocess Engineering ChE453 (2013, 2014, 2015, 2017);

Fluid Mechanics Transport 1 ChE367 (2013);

Metabolic Engineering ChE596 (2010, 2011, 2012);

International Experience EECE401 (2012 in Brazil);

Advanced Energy Lab EECE439 (2011)

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**Bioprocess Engineering **

Bioprocess Engineering
ChE 506

Classroom:
Sever Hall 300;
Tuesday and Thursday: 5:30~7:00 pm

Yinjie Tang (Instructor) Email: yinjie.tang@wustl.edu

Ryan Lee (TA, Brauer Hall 1047); Email: vitamincwater@gmail.com

Office: Brauer Hall 1025 (Phone:314-935-3441)

Office Hours for Dr. Tang: 4:30–5:30 Tuesday and Thursday

TA office hours (You can email TA and make an appointment)

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HW1 (Due Jan 26): Text Book: 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16

HW2 (Due Feb 9): 4.2, 4.3, 4.4, 4.6, 4.8, 4.10, 5.1, 5.3, 5.6, 5.7, 5.9, 5.11

HW3 (Due Feb 23): 3.2, 3.3, 3.5, 3.7, 3.9, 3.13, 3.16, 3.17

**
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**Process Control 401**

Class Time : 9–10 MWF ; Classroom : Lopata Hall 101 (Computer Lab in Ubuer 218); Help session : Whitaker 216 (7 – 8 pm, Tuesdays)

TA: Dishant Khatri; Email: dishant@wustl.edu; Brauer Hall 3039; Tolutola Oyetunde; Email: toyetunde@wustl.edu ; Brauer Hall 1042

**
Coverage: **
Model development and simplifications; Dynamics of first order and second order process
(including time delays); Determine the process features based on the roots of
characteristic equation; Draw and analyze systems using block diagram ; Develop transfer functions based on block diagram; Stability analysis and process safety ; P-I-D control features and design
; Feedforward ; Cascade control ; Simulink and MATLAB questions; Frequency responses

**Final Exam (Lopata Hall 101, 8-10am, Dec 16)**

**Coverage **

**1. Dynamics of first order and second
order process (including time delays) **

**2. Determine the process features based on
the roots of characteristic equation **

**3. Draw and analyze systems using block
diagram **

**4. Develop transfer functions based on
block diagram **

**5. Stability analysis, process safety and
Ruth array **

**6. P-I-D control features and design
**

**7. Feed forward and cascade control
**

**8. Simulink and MATLAB questions **

**9. Frequency responses **

**10. Class presentation questions **

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**Class in 2015: Bioprocess Engineering ChE 453 Classroom: Whitaker
216; Tuesday and Thursday: 10~11:30 am **

Tang Office: Brauer Hall 1025 (Phone:314-935-3441) Office Hours: 11:30–1:30 Tuesday and Thursday

TA: Wen Jiang (Brauer Hall 1044). TA office hour: 2~5pm, Monday

HW1: Text book, 1.2, 1.3, 2.2, 2.5, 2.6, 2.8, 2.10, 2.11, 2.14, 2.16, 3.1

HW2: 3.2, 3.3, 3.5, 3.7, 3.9, 3.13, 3.16, 3.17

HW3: 4.2, 4.3, 4.4, 4.6, 5.1, 5.3, 5.6, 5.7, 5.9, 5.11, 6.1, 6.3, 6.5, 6.9, 6.17(note: biomass yield Y = 0.4 g X/g S)

HW4: 7.2, 7.4, 7.5, 8.3, 8.7, 8.10, and Midterm Long Question 4 (using MATLAB to solve Fungal fermentation, you need to develop a model then use parameter fitting to find the model parameters).

HW5: 9.1, 9.2, 9.10, 9.12, 10.2; 10.15; 11.2 (Due April 7)

HW6: 12.3; 12.4; 12.5; 13.3; 14.3; 14.8; 16.1 (Due April 14)

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Fluid Mechanics (Transport 1, ChE367)

Tuesday and Thursday from 1pm-2:30pm (Classroom: Lopata 101); Office Hour (Brauer Hall 1025, 4~5pm, Monday)

Help Session: Brauer Hall 3015, 5:30pm-6:30pm Tuesday; Brauer Hall 3014, 5:30pm-6:30pm Wednesday

TA: Chris Oxford: Ph(314-935-7970), Email: coxford@wustl.edu; Mike Kuan-Yu Shen: Ph(314-935-7563), Email: kys9466@gmail.com

Class notes: Part 1; Part 2; Part 3

**Course Coverage**

9-3-2013 and before: Laminar vs turbulent flow; Reynolds number: Flow transition criteria; Friction factor: Darcy and Fanning definitions; Pipe roughness parameter; Friction factor charts: Some mathematical representations of the same; Pipe flow pressure drop calculations for a given flow; Pipe flow rate calculations given a pressure drop; Concept of fully developed flow; Relation between wall shear stress and pressure drop for a fully developed flow

9-5-2013: Newtonain vs non-Newtonain fluids; Bulk modulus; Speed of sound Mach number; Incompressibilty criteria; Surface tension; Contact angle; Level rise in a capillary; Laplace-Young equation; Pressure inside a bubble; Normal vs shear stress; Pressure as a scalar: Pascal’s law Equation of hydrostatics

9-10-13: Archimedus principle; Pressure variation in a column of gas; Pressure variation in a column of liquid; Pressure force on a plane surface; Center or pressure concept; Pressure force on a curved surface

9-12-13: Linear acceleration; Rigid body rotation; Compressible gas pressure with depth; Resultant force on a plane surface

9-17(19)-13: Newton second law; Streamlines in steady flow; Streamwise acceleration Normal acceleration; ;Newton’s law along a streamline; Bernoulli equation; Newton’s law normal to a streamline; Stagnation point and pressure

9-24-13 : Pressure profile in a tornado; Continuity equation; Pitot tube analysis; Free jet and draining of a tank; Flow meter equation; Sluice gate equation; Use of head balance; Head due to turbine or pump; Head due to friction

9-26-13 : Modified Bernoulli equation; Sudden expansion; Cavitation; Bernoulli for unsteady flow; Acceleration of a fluid particle: General derivation; Streamline calculation for 2-D steady state flows

10-1-13 : Oscillating manometer; Bernoulli for compressible fluids; Example: Working rate needed for a compressor; Macroscopic momentum balances; Sudden expansion revisited

10-3-13 : Jet flowing along a vane; Rocket acceleration analysis; Sluice gate momentum balance; Momentum correction factor; Angular momentum balance

10-8-13: Macroscopic balances examples

10-10-13 : Angular momentum: Examples; Energy equation; Converging-diverging nozzle

10-17-13 (Midterm in class, Open notes)

10-22-13: Velocity field, Eulerian and Lagrangian flow description, streakline/pathline/streamline, Steady flow

10-24-13: Acceleration field and unsteady effects, Concept of streamline coordinates

10-29-13: Reynolds Transport Theorem, Fluid element motion and deformation, Volumetric dilatation, Angular motion and fluid rotation/irrotation, Conservation of mass and continuity equation

10-31-13: Continuity equations for incompressible fluid, Cylindrical coordinate, Stream function/Streamlines, Conservation of linear Momentum (Euler's Equation of motion), The concept of the Navier-Stokes equation, Bernoulli Equation, Simplification of Navier-Stokes equation.

11-5-13: Velocity potential, Laplace equation, Source-sink pair, Simple solutions for fluids, Assumption of Bernoulli equation

11-12-13 : Model simplification via dimensionless variables, Re number, Froude number

11-14-13: Pipe flow, Laminar and Turbulent flow (By Chris)

11-19-13: Poiseuille's Law, Fully developed flow, Laminar flow pressure drop, Turbulent flow shear stress, Viscous sublayer, Dimensional Analysis of pipe flow

11-21-13: Turbulent velocity profiles (three regions), Turbulent pressure drop, Roughness, Major and minor head loss, Modified Bernoulli equation, Moody chart, Flow rate Measurement (orifice or nozzle meter)

11-26-13/Dec-3-13: Laminar and turbulent flow over immersed bodies; Life and Drag coefficients; Boundary layer definitions, Boundary layer separation, Effect of Re on Drag,

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**WUSTL and MSU are working together to improve
teaching in systems biology. **

Dolan KD, Tang YJ, Liao W “Improvement of Bioengineering Courses through Systems Biology and Bioprocess Modeling”. 121 Annual conference of American Society for Engineering Education. Indiana. 2014.

http://www.asee.org/public/conferences/32/registration/view_session?session_id=3412

**We shared Class Materials with
Dr. Wei Liao and Dr. Kirk Dolan from Michigan State**** University. More MATLAB
lectures can be found at the website below:**
**http://tang.eece.wustl.edu/MATLAB_WUSTL.htm**